Work

Design, synthesis, and in silico studies of new benzofuran–pyrazole hybrids as multi-kinase inhibitors with potential antiproliferative activity

Year: 2025

Type: article

Abstract: molecular docking and ADMET studies were performed on 3d to determine its expected binding interactions with the key regions in the kinase domains, as well as to ascertain its risks of human toxicity, drug-likeness traits, and oral bioavailability.

Source: RSC Advances

DOI: 10.1039/d5ra00553a

Authors: Somaia S. Abd El-Karim, Yasmin M. Syam, Reham M. Abdelkader, Mohamed K. El-Ashrey, Manal M. Anwar

Institutions: National Research Centre, German University in Cairo, Cairo University, King Salman International University

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042