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Antibacterial peptidomimetics based on guanidine-functionalized di-tertiary amides

Year: 2025

Type: article

Abstract: Tertiary amides such as peptoids are a novel class of peptidomimetics that offer enhanced structure, activity, and stability compared to many naturally occurring antimicrobial peptides.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d5md00688k

Authors: Ghayah Bahatheg, Rajesh Kuppusamy, Lissy M. Hartmann, Charles G. Cranfield, David StC. Black, Mark Willcox, Naresh Kumar

Institutions: UNSW Sydney, University of Jeddah, University of Technology Sydney

Language: English

Topic: Antimicrobial Peptides and Activities

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: hybrid

Funders: Bristol-Myers Squibb Foundation, University of New South Wales, Ministry of Education – Kingdom of Saudi Arabi, University of Jeddah, Australian Research Council

Award: New scaffolds for antimicrobial discovery

OpenAlex ID: W4414704667

FWCI: 0.928

Cites: 43

Cited by: 2

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