Effect of Sildenafil Citrate and Estradiol Valerate on Endometrial Thickness in Ovulation Induction With Clomiphene Citrate
Year: 2025
Type: article
Abstract: Background: Clomiphene citrate (CC) is the most commonly used oral agent for ovulation induction in anovulatory infertility.Despite its efficacy,CC has anti-estrogenic effects on the endometrium and cervical mucus,which may impair implantation. Strategies to overcome this drawback include adjuvant therapies such as estradiol valerate, which promotes endometrial proliferation, and sildenafil citrate, which enhances uterine blood flow and vascularity. Comparative data between these two adjuvants remain limited.
Authors: Tejal Madhukar Monika Patil, Ashutosh Vinay Bahulekar
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4414706104
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