Etio-pathogenetic aspects and clinical features of local signs of connective tissue dysplasia manifested with dentofacial anomalies in school-aged children
Year: 2025
Type: article
Abstract: The literature review presents the problems of congenital connective tissue disorders, characterized by multifactorial origins, associated with aggressive factors from the external and internal environment, manifesting as various general and local phenotypic traits. Anatomical-topographic changes in congenital collagenopathy of the organs and tissues of the oral cavity negatively impact the functional activity of the entire dental and jaw system, indicating their biological interconnection which correlates with each other. According to the results of the conducted studies, the most common dental and jaw anomalies in children and adolescents with dentofacial abnormalities are distal occlusion, narrowing and deformation of the dental-alveolar arches of the upper and lower jaws, and deep incisor overlap. As of today, the prevalence of dental and jaw anomalies does not show a tendency to decrease, and their combination with DSD in children and adolescents is insufficiently studied, which requires further research aimed at early detection of local phenotypic signs and improvement of socio-medical rehabilitation with an interdisciplinary approach.
Source: Yakut Medical Journal
Authors: M. M. Davydova, I. D. Ushnitsky, E. Yu. Nikiforova, T. V. Alekseeva, K. G. Piksaykina -Grigorieva, A. V. Ivanov
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4414708198