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Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

Year: 2025

Type: article

Abstract: Acinic cell carcinoma (AciCC) is an uncommon tumor of the salivary glands, with primary bronchogenic cases being particularly rare, especially in children. This report presents a case of a 3-year and 11-month-old boy who exhibited symptoms of cough and fever. Contrast-enhanced CT imaging revealed a solid mass in the right upper lung lobe accompanied by atelectasis, with poor bronchial visualization and no abnormal enhancement. Bronchoscopy identified a tumor obstructing the right upper lobe bronchial orifice. Surgical resection was performed, and histopathological analysis confirmed acinic cell carcinoma without lymph node involvement. The patient remained recurrence-free during an 18-month follow-up. Pediatric primary bronchial AciCC is exceptionally rare and typically manifests with non-specific symptoms. Radiological findings such as solid lung lesions or atelectasis may lead to misdiagnosis as pneumonia. However, complete surgical excision generally yields favorable outcomes.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1640216