Extraction Method and Solvent Effect on Antioxidant and Anti-lipase Activities of Nostoc sp. MRB-1 from the Peatlands in Oxbow Hanjalutung Lake, Indonesia
Year: 2025
Type: article
Abstract: The increasing utilization of microalgae as a natural resource of bioactive compounds encourages finding efficient and cost-effective ways to extract those compounds. Therefore, the present study aimed to evaluate two solvents and two extraction methods to obtain extracts of microalgae Nostos sp. MRB-1. The extracts were evaluated regarding phenolic content, antioxidant, and anti-lipase activities. The results showed that maceration using ethanol obtained the highest phenolic content (11.77±1.47 GAE mg/g dry extract) and anti-lipase activity with the value of 23.01±1.66% at 0.38 mg/mL. While the extract obtained from the ultrasound using hexane exhibited the highest antioxidant activity with a value of 39.68±0.07% at 0.8 mg/mL. These results demonstrate that maceration using ethanol is more effective for phenolic extraction from microalgae. In microalgae, phenolic content positively correlates with anti-lipase activity, but the opposite was verified, phenolic compounds are not contributors to the antioxidant activity of Nostoc sp. MR-1 extract
Source: INDONESIAN JOURNAL OF PHARMACY
DOI: 10.22146/ijp.15492
Language: English
Subfield: Aquatic Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $200
OpenAlex ID: W4414744461
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