Work

Monitoring Nitric Oxide in Trigeminal Neuralgia Rats with a Cerium Single-Atom Nanozyme Electrochemical Biosensor

Year: 2026

Type: article

Abstract: . Results demonstrated that NO concentration was associated with the TN onset. Following carbamazepine treatment, NO production from nerves decreased, accompanied by an alleviation of pain. These findings indicate that the biosensor serves as a valuable tool for investigating the pathogenesis of TN and guiding subsequent therapeutic strategies.

Source: ACS Sensors

DOI: 10.1021/acssensors.5c04286

Authors: Kangling Tian, Fuhua Li, Yuxuan Yang, Ran Chen, Shihong Chen, Wenbin Wei, Yihang Shen, Muzi Xu, Chunxian Guo, Luigi G. Occhipinti, Hong Bin Yang, Fangxin Hu

Institutions: Suzhou University of Science and Technology, Southwest Jiaotong University, Southwest University, Shanghai Jiao Tong University, Shanghai Ninth People's Hospital, University of Cambridge, Shandong University

Language: English

Topic: Electrochemical sensors and biosensors

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Jiangsu Provincial Department of Education, Qinglan Project of Jiangsu Province of China, Engineering and Physical Sciences Research Council, Natural Science Research of Jiangsu Higher Education Institutions of China

Awards: EPSRC Centre for Innovative Manufacturing in Large Area Electronics, G169997780, Design theory-based nanostructured leaf-vein networks for selective VOC sensing, G3448766433, G526968959, G6809462597

OpenAlex ID: W4414749113

FWCI: 3.385

Cites:

Cited by: 2

Related to: