Work

Disseminated brain Nocardia abscess with bronchial and esophageal fistulas

Year: 2025

Type: article

Abstract: Disseminated nocardiosis is a rare but life-threatening infection, with limited documented cases. Moreover, there have been no reports of Nocardia mediastinal abscess leading to bronchial or esophageal fistulae. We present a 62-year-old immunocompetent male with cerebellar and mediastinal abscesses caused by Nocardia beijingensis , complicated by both bronchial-mediastinal and esophageal fistulas. He received treatment including surgical intervention, endoscopic procedures, and antibiotic therapy. This case highlights the critical role of multidisciplinary collaboration in diagnosing and managing disseminated nocardiosis, particularly when rare complications arise. Early molecular diagnostics (next-generation sequencing, NGS) and individualized treatment adjustments were pivotal.

Source: IDCases

DOI: 10.1016/j.idcr.2025.e02362

Authors: Yunzhao Mo, Ruixin Yang, Gaici Xue, Dandan Fan, Hongmin Bai

Institution: Guangzhou University of Chinese Medicine

Language: English

Topic: Actinomycetales infections and treatment

Subfield: Microbiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,370