Work

Major phytoconstituents of temulawak (Curcuma xanthorrhiza) in hepatoprotective activity

Year: 2025

Type: article

Abstract: C. xanthorrhiza , commonly known as Javanese turmeric or temulawak in Indonesia, belongs to the Zingiberaceae family. C. xanthorrhiza is widely used to treat various health problems, including loss of appetite, gastrointestinal disorders, constipation, diarrhea, fever, arthritis, and liver dysfunction. In Indonesia, C. xanthorrhiza is widely recognized and traditionally used for liver disease treatment, although its hepatoprotective mechanisms were not scientifically validated in traditional practice. Current research has identified xanthorrhizol and curcuminoids (including curcumin and bisdemethoxycurcumin) as the primary active compounds in C. xanthorrhiza , which exert hepatoprotective effects through various studied mechanisms.

Source: Comptes Rendus Chimie

DOI: 10.5802/crchim.411

Authors: Jumardi Jumardi, Mohammad Wijaya

Institution: State University of Makassar

Language: English

Topic: Ginger and Zingiberaceae research

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414764587