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Characteristics Associated With Breakthrough Congenital Syphilis in Florida and Arizona, 2018–2022

Year: 2025

Type: article

Abstract: Congenital syphilis (CS) can occur despite timely identification and adequate treatment of maternal syphilis (breakthrough CS). We examined associations between maternal characteristics and prevalence of breakthrough CS. Having primary/secondary syphilis, a higher maximum nontreponemal titer, and treatment initiation closer to delivery were associated with a higher prevalence of breakthrough CS.

Source: Sexually Transmitted Diseases

DOI: 10.1097/olq.0000000000002249

Authors: Joshua Lassen, Breanne Anderson, Maegan Matter, Felicia M.T. Lewis, Nicole L. Davis, James Martin Matthias

Institutions: Florida Department of Health, Arizona Department of Health Services, Centers for Disease Control and Prevention

Language: English

Topic: Syphilis Diagnosis and Treatment

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4414791293

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