Work

Supplementary Methods and Tables from Late-Stage Outcomes as Surrogates for Mortality in Cancer Screening Trials: A Systematic Review and Meta-analysis

Year: 2025

Type: supplementary-materials

Abstract: Supplementary Methods and Tables: includes five sections. Section 1 outlines the comparison with previously published meta-analyses of mortality outcome surrogacy in cancer screening trials (including Table S1 and Table S2, and description of this work). Section 2 outlines the systematic searches in bibliographic databases and study selection (including Tables S3-S11 and description of this work). Section 3 provides detailed information on trials and the reported outcomes for the assessment of mortality outcome surrogacy (including Table S12-15, and a reference list for those four tables). Section 4 details the detailed meta-analytic results, including sensitivity and subgroup analyses (Including the methods that surround Figures S1-4, Table S16, Table S17). Section 5 includes selected aspects of limitations in the reported trial data (Table S19 and a description of this work).

DOI: 10.1158/1055-9965.30271514

Authors: Matejka Rebolj, Adam R. Brentnall, Julia Geppert, Nefeli Kouppa, Bethany Shinkins, Karoline Freeman, Chris Stinton, Matthew J. Randell, Samantha Johnson, Robert A. Smith, Peter Sasieni, Sam M. Janes, Ruth Etzioni, Stephen W. Duffy, Sian Taylor-Phillips

Language: English

Topic: Global Cancer Incidence and Screening

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4414796239

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