Work

3-in-one PD-1CAR Tregs: A bioengineered cellular therapy for target engagement, activation, and immunosuppression with reparative potential

Year: 2025

Type: article

Abstract: CAR Tregs as a unique therapy with both targeted suppression and tissue repair potential.

Source: iScience

DOI: 10.1016/j.isci.2025.113677

Authors: Shuyun Dong, Tianxiao Zhang, Yujia Zhai, Lauren C. Naatz, Noel G. Carlson, John W. Rose, Brian Evavold, Mingnan Chen

Institutions: University of Utah, VA Salt Lake City Healthcare System

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: University of Utah, National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: G1475621779, G3508847427, G7178335325, G9000278209, A 3-In-One Design of CAR Tregs for Robust Immunotolerance

OpenAlex ID: W4414805081

FWCI: 0.745

Cites: 72

Cited by: 2

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