Dengue diagnosis in Guinea in two returning travelers from Côte d’Ivoire: a case report
Year: 2025
Type: article
Study design: Case Report
Abstract: • Detection and identification in Guinea of dengue virus serotype 1 and 3 in returning travelers • Strengthened local laboratory capacity enhances Guinea’s disease surveillance • Supporting dengue surveillance is crucial for outbreak preparedness in West Africa • Research on dengue virus evolution and transmission dynamics in Guinea is needed Dengue’s true burden on the African continent is likely underestimated. The majority of cases originate from West Africa, mostly from Burkina Faso. We report here the detection in Guinea of two imported cases of dengue in travelers returning from Côte d'Ivoire, one fatal (case 1) and one mild (case 2). Case 1 lived in Côte d’Ivoire and was diagnosed during a trip in Conakry, Guinea, on 14 August 2023, nine days after symptoms onset. He died on 21 August of an illness related to severe dengue; dengue virus serotype 3 (DENV-3) was further identified. Case 2 was diagnosed in N’Zérékoré, forested region of Guinea, with serotype 1 (DENV-1) on 11 July 2024, two days after disease onset while returning from Côte d’Ivoire. He was hospitalized for nine days until full recovery. In-country phylogenetic analysis of case 2 DENV-1 revealed its linkage with urban dengue viruses known to circulate in West Africa. This timely detection, supported by enhanced diagnostics and genomic surveillance capacity in Guinea's laboratory network, highlights the need to pursue the strengthening of surveillance systems for early detection of emerging viral infections, and emphasizes the importance to further monitor dengue circulation dynamics in West Africa.
Source: IJID Regions
Authors: Jacob Camara, Youssouf Sidibé, Giuditta Annibaldis, Barré Soropogui, Sarah Ryter, Moussa Condé, Eugène Kolie, Ibrahim Nourdine, Bakary Sylla, Carolina van Gelder, Nils Peter Petersen, Mette Hinrichs, Mamadou Diouldé Barry, Soua Koulemou, Bely Sonomy, Mariame Traore, Kaba Keïta, Mamadou Saliou Sow, Mamoudou Conde, Kaba Keïta, Seydou Dia, Moke Fundji Jean Marie Kipela, Fanta Mady Kouyate, Sory Condé, Alimou Camara, Stephan Günther, Sophie Duraffour, Sanaba Boumbaly
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,380
OpenAlex ID: W4414806695