Year: 2025
Type: article
Study design: Case Report
Abstract: We report a rare case of IgG4-related disease (IgG4-RD) presenting with retroperitoneal fibrosis and autoimmune pancreatitis, followed by sequential development of papillary thyroid carcinoma and diffuse large B cell lymphoma. Histopathologic and positron emission tomography-computed tomography findings were essential for diagnosis and guided timely treatment. This case highlights the potential oncogenic link between chronic IgG4-driven inflammation and B cell malignancy, emphasizing the need for vigilant cancer surveillance in patients with IgG4-RD.
Source: ACR Open Rheumatology
DOI: 10.1002/acr2.70114
Authors: Ji Li, Ming Zhang, Juanjuan Song, Lina Zhang, Sheng‐Guang Li
Institution: Peking University International Hospital
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,550
OpenAlex ID: W4414809651