Work

Syntheses of Pyrene-4,5-dione and Pyrene-4,5,9,10-tetraone

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide Improved gram scale synthesis procedures for the preparation of pyrene-4,5-dione and pyrene-4,5,9,10-tetraone are reported. Pyrene-4,5-dione has been synthesized using potassium persulfate as the oxidant and RuO 2 · n H 2 O as the catalyst in the biphasic CH 2 Cl 2 /H 2 O solvent mixture containing K 2 CO 3 as the base. We also developed several procedures for multigram scale oxidation of pyrene-4,5-dione to pyrene-4,5,9,10-tetraone, eliminating the need for chromatographic purification of the poorly soluble tetraone product.

Source: The Journal of Organic Chemistry

DOI: 10.1021/acs.joc.5c01542

Authors: Omolola Balogun, Besan Khader, Tetyana Ignatova, Aleksandrs Prokofjevs

Institutions: North Carolina Agricultural and Technical State University, University of North Carolina at Greensboro

Language: English

Topic: Oxidative Organic Chemistry Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funder: Air Force Office of Scientific Research