Work

Design and validation of the first-in-class PROTACs for targeted degradation of the immune checkpoint LAG-3

Year: 2025

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2025.130428

Authors: Nelson García Vázquez, Somaya A. Abdel-Rahman, Hossam Nada, Moustafa Gabr

Institutions: Weill Cornell Medicine, Mansoura University

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Elsa U. Pardee Foundation

Award: G6569341726

OpenAlex ID: W4414825924

FWCI: 0.504

Cites: 20

Cited by: 2

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