Work

Development of Dual FLT3 and CHK1 PROTACs for the Treatment of AML

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02332

Authors: Xuanmin Lian, Yue Gao, Wenjing Du, Chengcheng Xu, Xiaowu Dong, Jinxin Che, Yubo Zhou, Jia Li, Tao Liu

Institutions: Zhejiang University, Nanjing University of Chinese Medicine, Chinese Academy of Sciences, Shanghai Institute of Materia Medica

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Key Research and Development Program of Zhejiang Province

Award: G7585206375

OpenAlex ID: W4414830270

FWCI: 1.044

Cites: 42

Cited by: 4

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