Work

Analytical cohort study on intraoperative hypotension as a risk factor for postoperative acute kidney injury

Year: 2025

Type: article

Abstract: Acute kidney injury (AKI) is a serious complication that happens after surgery and intraoperative hypotension (IOH) is a modifiable risk factor. We did a cohort analytical study consisting of 145 adult patients who were undergoing major non-cardiac surgery under general anesthesia. Patients who were diagnosed with IOH (defined as mean arterial pressure <65 mmHg for ≥15 minutes), had significantly higher rates of postoperative AKI. Multivariate analysis confirmed independent predictors of AKI including IOH, chronic kidney disease, and prolonged operative time. Overall, this study highlights the importance of hemodynamic monitoring and the continuing maintenance of MAP ≥65 mmHg as a potential way to reduce renal complications.

Source: Bioinformation

DOI: 10.6026/973206300213223

Authors: Vishal Mruthyunjaya Kalmani, Dhyaneshwar Ra, Yeruva Bheemeswara Reddy, Poornima Venkatraman

Institutions: Barking, Havering And Redbridge University Hospitals NHS Trust, Stanley Medical College, Davao Medical School Foundation

Language: English

Topic: Acute Kidney Injury Research

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4414845529