Work

Colloidal Interactions in Simulated Intestinal Fluids: Implications for Oral Drug Delivery at the Nanoscale

Year: 2025

Type: article

Abstract: Oral Drug Delivery Nanoparticles in action! In article number 2500350, Juliane Fjelrad Christfort, Matteo Tollemeto, and co-workers illustrate how bile salts and lipids in simulated intestinal fluids shape particle behavior. These components govern properties from aggregation to mucoadhesion and cytotoxicity, revealing the underlying mechanisms that control nanoparticle performance in the gut and affect drug delivery effectiveness.

Source: Small Science

DOI: 10.1002/smsc.70106

Authors: Juliane Fjelrad Christfort, Matteo Tollemeto, Yudong Li, Lasse Højlund Eklund Thamdrup, Jan van Hest, Anja Boisen

Institutions: Danish National Research Foundation, Technical University of Denmark, Eindhoven University of Technology

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $6,350