Work

Síntese de Amidas Derivadas do Ácido 6α,7β-Di-hidroxivouacapan-17β-óico Isolado dos Frutos de Pterodon polygalaeflorus Benth (Leguminosae)

Year: 2001

Type: article

Abstract: Hydro alcoholic infusions from fruits of Pterodon polygalaeflorus Benth, commonly known as “Sucupira-Branca", are used in Brazilian folk medicine for rheumatic problems and throat infections. Since it has been verified that furanediterpene 6α,7β-di-hydroxyvouacapan-17β-oic acid (ADV), isolated from the hexane extract of these fruits, presents anti-inflammatory, analgesic, and plant growth regulatory activity, a variety of ADV derivatives has been synthesized with the aim of obtaining more information about the structure-activity relationships of this series of compounds. In this work four new amide (4-7) derivatives of ADV have been synthesized. Their structures were established by spectroscopic data, including 2D-NMR methods.

Source: Revista Brasileira de Plantas Medicinais

DOI: 10.70151/5cj6d119

Authors: A. L. Teixeira, V. J. Belinelo, G. M. Stefani, G. T. Reis, D. L. Ferreira-Alves, D. Piló-Veloso

Institutions: Universidade Federal de Minas Gerais, Universidade de Itaúna

Language: English

Topic: Bioactive Natural Diterpenoids Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $57