Work

Molecular characterization of BMP15 and BMPR-IB genes in Algerian D’man and Ouled Djellal sheep populations, using RFLP-PCR and AS-PCR techniques

Year: 2025

Type: article

Abstract: Background: In Algeria, the sheep farming industry provides a crucial source of red meat. However, to meet the growing domestic demand, improvements in flock prolificacy are required. Aim: To investigate polymorphisms in the BMP15 and BMPR1B genes in two Algerian sheep breeds, D’man and Ouled Djellal, in order to identify their potential influence on prolificacy. Methods: The genotyping techniques PCR-RFLP and allele-specific PCR were used to examine the FecXI and FecXBar mutations in the BMP15 gene, and the FecBB mutation in the BMPR1B gene. Results: The genetic analysis failed to reveal these mutations in the Algerian sheep populations studied. Conclusions: This finding underscores the need to explore other genetic factors, including known or novel mutations, which could potentially affect prolificacy in these local sheep breeds. By identifying other factors, specific markers could be developed for more targeted breeding programs. This could open new avenues for research and improve our understanding of the genetic basis of prolificacy in Algerian sheep breeds.

Source: Revue d’élevage et de médecine vétérinaire des pays tropicaux

DOI: 10.19182/remvt.37717

Authors: Assia Hadjazi, Fatima Zohra Mahammi, Nacera Tabet-Aoul

Institutions: Université des Sciences et de la Technologie d'Oran Mohamed Boudiaf, Ecole Supérieure en Sciences Biologiques d’Oran, Université Oran 1 Ahmed Ben Bella

Language: English

Topic: Genetic and phenotypic traits in livestock

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Zero hunger

Open Access status: diamond

Funders: Région Occitanie Pyrénées-Méditerranée, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement