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Normogonadotropic azoospermia: the puzzle of hormonal treatment

Year: 2025
Type: article
Abstract: The editorial proposes an original algorithm for hormonal treatment of patients with normogonadotropic azoospermia (NOAN). This condition is very common in clinical practice, and the approach of endocrinologists varies. Different therapeutic strategies are recommended based on clinical (testicular volume and body mass index) and hormonal parameters (inhibin B and 17-alpha hydroxyprogesterone levels). The algorithm suggests the role of follicle-stimulating hormone or chorionic gonadotropin, or incretin therapy, which are fully included in the potential therapeutic proposal due to the significant repercussions of metabolic syndrome and obesity on sperm quality.
Language: English
Field: Medicine
Open Access status: bronze
OpenAlex ID: W4414914021
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