Work

Understanding the influence of temporary neurologic dysfunction in the outcomes of aortic surgery

Year: 2025

Type: article

Abstract: Objective: Temporary neurologic dysfunction (ND) is common after aortic surgery. The Valve Academic Research Consortium 3 classifies ND as NeuroARC Type 1 (stroke), Type 2 (covert injury), and Type 3 (transient ischemic attack/delirium without injury). This study applies these definitions to aortic surgery, focusing on Type 3. Methods: A single-center retrospective analysis of adult patients with open thoracic aortic surgery from March 2005 to December 2023 was performed. Primary end points were mortality and major postoperative complications (reoperation for bleeding, respiratory failure, and acute renal failure). Propensity score weighting using overlap weights balanced covariates between Type 3 and no ND groups. Kaplan-Meier curves and Cox regression analyzed mortality. Multivariable logistic regression identified factors associated with Type 3 ND. Results: < .001). Conclusions: Type 3 occurs in about 10% of cases and is associated with in-hospital complications but not mortality. Identified risk factors may aid in prevention.

Source: JTCVS Open

DOI: 10.1016/j.xjon.2025.09.031