Work

Mortality in craniopharyngiomas: Data from the last two decades

Year: 2025

Type: article

Abstract: Craniopharyngiomas are rare epithelial tumours arising along the path of the craniopharyngeal duct. They are histologically benign but potentially clinically aggressive tumours due to their invasive behaviour and high recurrence rates. Patients with craniopharyngioma have a high burden of comorbidities which could affect their long-term survival. Studies published in the last 20 years and reporting on standardized mortality ratios (SMR) have demonstrated high mortality (SMRs ranging between 2.45 and 12.2), as also proposed in older reports. Cardiovascular, respiratory diseases and infections are main causes of death. Apart from older age at diagnosis, data on other predictors of mortality are not consistent requiring further elucidation.

Source: Best Practice & Research Clinical Endocrinology & Metabolism

DOI: 10.1016/j.beem.2025.102049

Authors: Georgia Ntali, Abdul Muktadir Shafi, Niki Karavitaki

Institutions: University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital Birmingham, Evangelismos Hospital, Endo-ERN, University of Birmingham

Language: English

Topic: Pituitary Gland Disorders and Treatments

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,450