Hydatidiform mole incidence in Lombardy, northern Italy, 2009–2022: continued decline or plateau?
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction Hydatidiform mole (HM) incidence has shown contrasting temporal trends across different regions.Methods We analyzed HM incidence in Lombardy, Italy, from 2009 to 2022. HM cases were identified through regional registry data.Results A total of 1,131 HM cases occurred among 1,471,567 pregnancies, averaging 77 cases per 100,000 pregnancies. A significant decline was observed between 2009 and 2015 (p = 0.01), but no consistent trend emerged over the full period (p = 0.76). HM incidence was highest in women aged ≥46 (699.1/100,000) and <20 (107.6/100,000), and among women of Asian origin (110.4/100,000).Discussion The study suggests that diagnostic practices and demographic shifts may have influenced HM trends, while also confirming persistent ethnic and age-related risk patterns.
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Funder: European Commission
Award: G972786147
OpenAlex ID: W4414921017