Year: 2025
Type: article
Abstract: Mechanosensation plays a key role in many physiological processes. Despite its importance, high-content methods for studying mechanosignaling at the cell level remain challenging. This article presents an approach to assess mechanosignaling in adherent cells using isotropic mechanical stretch combined with real-time Ca2+ fluorescence imaging. This method integrates our IsoStretcher platform with image registration, cell segmentation, and single-cell and population-based Ca2+ signaling analysis.
Source: BIOspektrum
Institution: Friedrich-Alexander-Universität Erlangen-Nürnberg
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,190
OpenAlex ID: W4414924764