Work

EXIT-Strategien intrazellulärer Parasiten im Visier hochauflösender Bildgebung

Year: 2025

Type: article

Abstract: Living inside host cells provides significant advantages for human parasites like Plasmodium and Leishmania. Nevertheless, to complete their life cycle, they must eventually exit the host cell – a critical step that represents an attractive target for drug development. However, achieving the necessary combination of high spatial and temporal resolution imaging to capture egress dynamics remains a challenge and software pipelines for data analysis need to be advanced. Addressing these challenges will be key to unlocking the exit strategies of parasites.

Source: BIOspektrum

DOI: 10.1007/s12268-025-2567-9

Authors: Gabriele Pradel, Friedrich Frischknecht

Institutions: RWTH Aachen University, Heidelberg University, University Hospital Heidelberg

Language: English

Topic: Cell Image Analysis Techniques

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,190