Year: 2025
Type: review
Study design: Systematic Review
Abstract: This systematic review explores the relationship between digital biomarkers, measured using wearable devices, and fatigue in patients with chronic diseases. Studies included in this review focused on individuals with diseases or conditions in 13 broad categories: multiple sclerosis (MS); rheumatoid arthritis (RA); chronic obstructive pulmonary disease (COPD); long COVID; cancer; chronic fatigue syndrome (CFS); pulmonary sarcoidosis; Parkinson's disease; chronic stroke; chronic inflammatory rheumatic disease (CIRD); Inflammatory Bowel Diseases (IBD), Primary Sjogren's Syndrome (PSS), and Systemic Lupus Erythematosus (SLE). The review synthesizes findings on the correlation between objective digital biomarkers and self-reported fatigue, highlighting the potential for disease-specific digital biomarkers to inform personalized fatigue management. The results suggest that reduced physical activity, increased sedentary behavior and autonomic dysfunction are associated with fatigue levels across multiple disease conditions included in this review, though the strength of this association and the specific biomarkers involved vary across diseases.
Source: npj Digital Medicine
Language: English
Subfield: Computer Vision and Pattern Recognition
Field: Computer Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $4,090
Funders: Health Research Board, UK Research and Innovation, National Institute for Health and Care Research, Department of Health and Social Care, Newcastle University, Newcastle upon Tyne Hospitals NHS Foundation Trust, Engineering and Physical Sciences Research Council, NIHR Newcastle Biomedical Research Centre, Cooperative Research Facility Center, Toyohashi University of Technology
Awards: G1599339886, Transforming the Objective Real-world measUrement of Symptoms (TORUS), Transforming Parkinson's disease clinical management with integrated digital health technologies, Northern Health Futures Hub, G5326905627, G7449636305, Beyond remission: novel strategies to optimise shared decisions on drug tapering in rheumatoid arthritis
OpenAlex ID: W4414927975