Work

Prenatal vitamin D status and long-term neurocognitive outcomes: building on an emerging evidence base

Year: 2025

Type: article

Abstract: Vitamin D sufficiency during pregnancy has long been recognized for its importance in fetal bone development. Still, a growing body of evidence is shedding light on its broader role in neurodevelopment. 1 , 2 , 3 , 4 , 5 , 6 The recently published manuscript by Valera-Gran et al. in Pediatric Research contributes meaningfully to this evolving field. 7 Drawing on the ECLIPSES cohort, a prospective study of pregnant women and their offspring in Catalonia, Spain, the authors present compelling evidence that higher maternal 25-hydroxyvitamin D [25(OH)D] concentrations during pregnancy are positively associated with improved neurocognitive outcomes in children at four years of age. These findings reinforce earlier reports and offer new insights into the importance of trimester-specific maternal vitamin D status on child development.

Source: Pediatric Research

DOI: 10.1038/s41390-025-04476-1

Authors: Carol L. Wagner, Bruce W. Hollis

Institution: Medical University of South Carolina

Language: English

Topic: Vitamin D Research Studies

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,390