Automated classification of cellular expression in multiplexed imaging data with Nimbus
Year: 2025
Type: article
Source: Nature Methods
Authors: Josef Lorenz Rumberger, Noah F. Greenwald, Jolene S. Ranek, Potchara Boonrat, Cameron Walker, Jannik Franzen, Sricharan Reddy Varra, Alex Kong, Cameron Sowers, Candace C. Liu, Inna Averbukh, Hadeesha Piyadasa, Rami Vanguri, Iris Nederlof, Xuefei Julie Wang, David Van Valen, Marleen Kok, Sean C. Bendall, Travis J. Hollmann, Dagmar Kainmueller, Michael Angelo
Institutions: Max Delbrück Center, Humboldt-Universität zu Berlin, Stanford Medicine, Stanford University, Charité - Universitätsmedizin Berlin, New York University, The Netherlands Cancer Institute, California Institute of Technology, Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, University of Potsdam
Language: English
Subfield: Biophysics
Domain: Life Sciences
Open Access status: green
Funders: U.S. Department of Defense, U.S. Department of Health and Human Services, Bill and Melinda Gates Foundation, Cancer Research Institute, Breast Cancer Research Foundation, Wellcome Trust, Deutscher Akademischer Austauschdienst, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of Allergy and Infectious Diseases
Awards: RELATING THE INTERPLAY OF TUMOR FUNCTION AND HOST RESPONSE TO CLINICAL OUTCOME IN TRIPLE NEGATIVE BREAST CANCER, The Phenotypic Landscape of Cognitive Decline as Revealed by Next-Generation Multiplexed Ion Beam Imaging, G324707347, G3440579629, G3693813942, Predictive signatures in breast cancer using multiplexed ion beam imaging, [18F]-AraG -PET imaging to evaluate immunological response to checkpoint inhibitor therapy (CKI) in patients with advanced solid tumors, Comprehensive profiling of the tumor microenvironment to predict patient response to immunotherapy, MIRIAD - Multiplexed Imaging of Resilience In Alzheimers Disease, G5091744366, Macrophage phenotype polarization in clinical neoplasia, G5601930256, A robust platform for multiplexed, subcellular proteomic imaging in human tissue, G6988316663, Modeling the Role of Lymph Node Metastases in Tumor-Mediated Immunosuppression, G726778916, Uncoupling Age- Versus Cognitive-Related Cellular Senescence in Alzheimer's Disease, G7697764, G7810735352, G9000108373, G9000293380, G9000305977, Multimodal histologic atlas of human bone marrow, Stanford Cancer Immune Monitoring and Analysis Center (CIMAC), USING DEEP MUTATIONAL SCANNING TO CHARACTERIZE TUMOR-IMMUNE INTERACTIONS, Innate-adaptive immune bridging in gravidity-dependent immunity against placental malaria: a multi-omics approach
OpenAlex ID: W4414930807
