Work

Cryo-EM structure of the yeast Saccharomyces cerevisiae SDH provides a template for eco-friendly fungicide discovery

Year: 2025

Type: article

Abstract: (96 h) = 1.01 mg a.i./L). This study elucidates the structure of fungal SDH and demonstrates the potential of ScSDH for rational design of next-generation fungicides, addressing fungal resistance and environmental toxicity in agriculture.

Source: Nature Communications

DOI: 10.1038/s41467-025-64001-0

Authors: Zhi-Wen Li, Yuan-Hui Huang, Ge Wei, Zong-Wei Lu, Yu-Xia Wang, Guang-Rui Cui, Jun-Ya Wang, Xin-He Yu, Yi-Xuan Fu, Er-Di Fan, Qiong-You Wu, Xiao-Lei Zhu, Ying Ye, Guang-Fu Yang

Institution: Central China Normal University

Language: English

Topic: Fungal Plant Pathogen Control

Subfield: Ecology, Evolution, Behavior and Systematics

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $6,990

Funders: Jiangsu Academy of Agricultural Sciences, National Natural Science Foundation of China, National Key Research and Development Program of China

Awards: G6630121638, G7091989178

OpenAlex ID: W4414931940

FWCI: 14.88

Cites: 61

Cited by: 16

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