Work

Multimodal Imaging of Papillary Muscle-Origin Left Ventricular Myxoma

Year: 2025

Type: article

Abstract: BACKGROUND: Cardiac myxomas most commonly originate in the left atrium, whereas occurrences in the ventricles are rare, accounting for only 3% to 4% of cases. Their pseudoinvasive growth, which can mimic malignancy, poses significant diagnostic challenges. CASE SUMMARY: = 7.8) on positron emission tomography/computed tomography. Histopathological examination confirmed the mass as a benign myxoma with pseudoinvasive entrapment of the papillary muscle. Subtotal resection was performed, successfully maintaining mitral valve integrity. DISCUSSION: This case demonstrates the value of integrated imaging techniques in differentiating pseudoinvasive cardiac myxomas from malignant tumors, thereby enhancing diagnostic approaches for ventricular masses. TAKE-HOME MESSAGES: Multimodal imaging is crucial for diagnosing cardiac tumors located in atypical regions. Recognizing benign pseudoinvasive patterns is key to avoiding unnecessary radical surgery.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.105602