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Ionizable Lipid Nanoparticles for mRNA Delivery: Internal Self-Assembled Inverse Mesophase Structure and Endosomal Escape

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Year: 2025
Type: article
Source: Accounts of Chemical Research
DOI: 10.1021/acs.accounts.5c00522
Authors: Haitao Yu, Brendan P. Dyett, Calum J. Drummond, Jiali Zhai
Institution: RMIT University
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Australian Institute of Nuclear Science and Engineering, RMIT University, State Government of Victoria, Department of Education and Training, Australian Research Council
Awards: G1096673958, G1109510496, G1490361836, G3700300146, Deciphering lipid-RNA nanocarrier structure upon RNA complexation, G5024562517, Crossing restrictive biobarriers with self-assembled lipid nanocarriers
OpenAlex ID: W4414938111
FWCI: 9.388
Cites: 68
Cited by: 37
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