Intracarotid Platelet Rich Plasma In Sub-Acute Ischemic Stroke Cases (From 5th To 21st Post Stroke Day) - Pilot Study In 6 Cases Gives No Effect
Year: 2025
Type: article
Abstract: Background: Tissue Plasminogen Activator (tPA) showed a level 1 benefit in acute stroke (within 4.5 hours).But for more than 4.5 hours cases (if they fail to qualify for clot retrievers within 12 hours), autologous Intracarotid/Intraarterial Platelet rich plasma (PRP) is used here to provide growth factors at the cyton level to maintain and restore the raw materials for the synaptic flow.Aims/Study Design: PRP provides growth factors at the cyton level are the basis of the authors' hypothesis to treat sub-acute stroke cases from 5th day to 21st day.Pilot study on 6 cases prospective study. Materials and Methods:The human population included 6 sub-acute ischemic stroke patients from 5th to 21st post stroke day.The mean time for superfusion was 8 days post-stroke.Pre-and post PRP status was monitored by NIHSS, MRI-DWI and ALTENS.Results: After 2 hours of PRP, the mean change in the NIHSS score was no change in NIHSS, ALTENS or MRI-DWI in LACS, PACS, TACS or POCS.Conclusions: PRP alone via intracarotid do not cause improvement in neurological deficit in these 6 cases.
Source: Acta Scientific Neurology
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414947340
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