Work

Successful Treatment of Severe Purpura Fulminans With Anakinra

Year: 2025

Type: article

Abstract: Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities. The management of PF requires a comprehensive approach, including the treatment of the underlying infection, anticoagulation, and anti-inflammatory therapy. Herein we present the case of a child with severe PF successfully treated with anakinra, an anti-IL1-receptor monoclonal antibody.

Source: Pediatric Dermatology

DOI: 10.1111/pde.70034

Authors: Francesco Zulian, Luca Spiezia, Antonio Amabile, Francesca Tirelli, Alessandra Meneghel

Institutions: University of Padua, Azienda Ospedale - Università Padova

Language: English

Topic: Streptococcal Infections and Treatments

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,920