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Coexistence of Systemic Lupus Erythematosus and Acute Myeloid Leukemia: A Complex Clinical Case

Year: 2025

Type: article

Abstract: This case presentation explores the rare coexistence of systemic lupus erythematosus (SLE) and acute myeloid leukemia (AML) in a single patient, highlighting the diagnostic and therapeutic challenges faced in managing both conditions.Autoimmune diseases, particularly rheumatic disorders, have been linked to myeloid neoplasms, with varying prevalence rates.The patient exhibited symptoms of pancytopenia, leading to the diagnosis of AML confirmed by myelogram findings, including Auer bodies and a translocation (8;21).The management approach involved a multidisciplinary strategy, incorporating corticosteroids for SLE and chemotherapy for AML, while addressing the risk of infection.This case underscores the importance of recognizing the interplay between autoimmune diseases and hematological malignancies, necessitating a careful balance in treatment to optimize patient outcomes.

Source: Medical & Clinical Case Reports Journal

DOI: 10.51219/mccrj/kashif-ali/336

Authors: Kashif Ali, Muhammad Hassan, Hibba Aziz, Abdul Rauf, Javaria Ismail, Abubaker Khan

Institutions: Lady Reading Hospital, Hayatabad Medical Complex, People's University of Medical and Health Sciences for Women, Chandka Medical College

Language: English

Topic: Systemic Lupus Erythematosus Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4414967638

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