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Opioid-Free Total Intravenous Anesthesia in a Schizophrenia Patient with Retrosternal Goiter

Year: 2025

Type: article

Abstract: Introduction: Schizophrenia patients on serotonergic antipsychotics risk serotonin syndrome (SS) with opioids or 5-HT3 antagonists, alongside postoperative delirium and respiratory compromise related to Opioids.Green anesthesia minimizes environmental risks.Case report: A female in her early 40s with schizophrenia and type 2 diabetes, on Aripiprazole, Quetiapine and Trihexyphenidyl, underwent thyroidectomy for a retrosternal goiter using opioid-free Total Intravenous Anesthesia (TIVA), avoiding Granisetron to reduce SS risk.No tracheomalacia or PONV occurred; minimal analgesics were needed, declined post-op.Discussion: This approach prevented SS, delirium, cognitive decline and respiratory complications by avoiding opioid and 5-HT3 receptor interactions.Conclusion: Opioid-free TIVA is safe and sustainable for high-risk patients.

Source: Medical & Clinical Case Reports Journal

DOI: 10.51219/mccrj/yousef-almassalmeh/333

Authors: Yousef Almassalmeh, Ayman A. Abdellatif

Institution: King Saud University

Language: English

Topic: Anesthesia and Sedative Agents

Subfield: Anesthesiology and Pain Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4414967643

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