Year: 2025
Type: article
Abstract: The present study was conducted to learn about the various pathological changes due to folic acid-induced Renal changes in mice, which is a widely used experimental model to study the mechanisms underlying kidney fibrosis. Following high-dose folic acid administration, acute kidney injury is rapidly induced, primarily affecting the tubular epithelium. Clinical pathology, macroscopic, and microscopic changes with Hematoxylin & Eosin and special stains such as Masson Trichrome Stain fibrous tissue proliferation. Along with fibronectin, α-SMA, and Smad expression in the progression of Kidney fibrosis. Taken together, our findings might serve as a rationale for developing prospective innovative renal fibrosis. This present study's finding serves as a pathological change with the marker identification, affecting Renal disease progression.
DOI: 10.56093/kqvtzc46
Author: V.M. Prajapati
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4414970000
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