Work

Efficacy and Safety of Oral PCSK9 Inhibitors in Adults with Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Year: 2025

Type: preprint

Study designs: Systematic Review, Meta-Analysis

Abstract: Background: Hypercholesterolemia is a key modifiable risk factor for atherosclerotic cardiovascular disease (ASCVD). Injectable PCSK9 inhibitors lower LDL-C effectively but are limited by cost and parenteral administration. Oral PCSK9 inhibitors have

DOI: 10.22541/au.175999156.65770492/v1

Authors: Amna Amir Jalal, Syed Ibad Hussain, Erum Siddiqui, Muhammad Saad Khan, Muhammad Burhan, Ali Jawwad Karim, Rabia Nizam, Mahrukh Amir

Institutions: Jinnah Sindh Medical University, Dow University of Health Sciences, Bahria University

Language: English

Topic: Lipoproteins and Cardiovascular Health

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4414974352

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