Work

Real‐Time Monitoring of DNA Origami‐Cell Interactions via Single Particle Tracking (Small 40/2025)

Year: 2025

Type: article

Abstract: DNA Origami In article number 2502496, Tania Patiño Padial and co-workers highlights real-time single-particle tracking of ligand-functionalized DNA origami nanorods interacting with cell membranes. Leveraging the spatial programmability of DNA origami, this approach enables precise interrogation of receptor-ligand binding kinetics and dynamics at the cell surface, offering new insights into nanoscale biointerfaces with high spatial and temporal resolution.

Source: Small

DOI: 10.1002/smll.70742

Authors: Indra Van Zundert, Elena Spezzani, Roger R. Brillas, Lars Paffen, Angelina Yurchenko, Tom F. A. de Greef, Lorenzo Albertazzi, Alessandro Bertucci, Tania Patiño Padial

Institutions: Eindhoven University of Technology, University of Parma

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W4414974610

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