Work

Preparation, characterization and application of MT@SP@GBP and their use for synthesis of novel pyrazolophthalazine-5,10-diones

Year: 2025

Type: article

Abstract: A series of azo-linked pyrazolophthalazine-5,10-diones (APPDs) were synthesized via multicomponent reaction of phthalic anhydride, synthetized azo-aldehyde, malononitrile, and hydrazine hydrate using the gabapentin (GBP) functionalized silica coated Fe 3 O 4 magnetic nano composites (MT@SP@GBP MNCs) as a catalyst. All derivatives were characterized by FT-IR, 1 H NMR, 13 C NMR, and mass spectrometry. MT@SP@GBP MNCs was characterized by FT-IR, FE-SEM, TEM, TGA, XRD, EDX and VSM.

Source: Scientific Reports

DOI: 10.1038/s41598-025-19325-8

Authors: Zahra Alizadeh, Mohammad Nikpassand, Masoud Mokhtary, Leila Zare Fekri

Institutions: Islamic Azad University Rasht Branch, Payame Noor University

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,690

Funder: Islamic Azad University