Work

Risk of Clostridioides difficile Infection After Helicobacter pylori Treatment in a Large Population in the United States

Year: 2025

Type: article

Abstract: Background and Aims: infection (CDI). Methods: treatment and evaluated the predictors of CDI using multivariable logistic regression. Results: treatment was 2.00 (1.02-3.90) overall, 3.15 (1.14-8.70) for concomitant therapy, and 6.34 (2.75-14.59) for bismuth quadruple therapy. Inflammatory bowel disease (IBD) (aOR, 7.89 [2.38-26.21]) and history of CDI (aOR, 8.27 [1.92-35.62]) had the strongest association with CDI, while Asians/Pacific Islanders (aOR, 0.22 [0.09-0.55] and non-English language preference (aOR, 0.30 [0.12-0.72]) were associated with a lower risk. Conclusion: among individuals with IBD or a prior history of CDI.

Source: Gastro Hep Advances

DOI: 10.1016/j.gastha.2025.100832

Authors: Lawrence J. Leung, Sophie A. Merchant, Jessica M. Badalov, Douglas A. Corley, Dan Li

Institutions: Kaiser Permanente Northern California, Kaiser Permanente

Language: English

Topic: Clostridium difficile and Clostridium perfringens research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000