Year: 2025
Type: article
Study design: Case Report
Abstract: Adult-onset Still’s disease (AOSD) is a rare polygenic systemic autoinflammatory disease of unknown etiology, characterized by neutrophilic leukocytosis and the absence of rheumatoid factor and antibodies to cyclic citrulline-containing peptide in the blood serum. Lung damage in AOSD is a rare but serious complication. Bronchiolitis, bronchitis, nonspecific interstitial pneumonia, and organizing interstitial pneumonia have been described as patterns of lung damage in AOSD. Pulmonary manifestations of AOSD remain poorly understood. The aim of the article was to demonstrate a clinical case of AOSD, the main manifestation of which was the development of cryptogenic organizing pneumonia with respiratory failure. The article presents in detail the stages of the diagnostic search. An interesting feature of this clinical case was the absence of the most common symptoms of AOSD (sore throat, arthritis/arthralgia). Conclusion. This clinical case emphasizes the importance of clinicians’ awareness of possible pulmonary complications in AOSD.
Source: PULMONOLOGIYA
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4414996079