Work

Modulation of poststroke motor cortex activity by metaplasticity-inducted theta burst stimulation: A concurrent TMS-EEG study

Year: 2025

Type: article

Abstract: Metaplasticity is a high-level form of plasticity mechanism which describes how prior neuronal activity level mediates subsequent Hebbian-type synaptic plasticity induction, that is, long-term depression (LTD) or long-term potentiation (LTP) [1]. The pairing of two non-identical repetitive transcranial magnetic stimulation (rTMS) protocols could enlarge after-effects (either LTP- or LTD-like) in human primary motor cortex (M1) presumably via metaplastic mechanisms. The pairing protocol is called priming stimulation, or metaplasticity-inducted stimulation [1,2].

Source: Brain stimulation

DOI: 10.1016/j.brs.2025.10.008

Authors: Jack Jiaqi Zhang, Roy Rongyue Zeng, Michael Tang, Zhongfei Bai, Ruixuan Lin, Youxin Sui, Yongan Gong, Tommy LH. Lam, David MA. Mehler, Ulf Ziemann, Kenneth NK. Fong

Institutions: Hong Kong Polytechnic University, Queen Mary Hospital, Tung Wah Hospital, Tongji University, Shanghai Sunshine Rehabilitation Center, Universitätsklinikum Aachen, RWTH Aachen University, University of Münster, Hertie Institute for Clinical Brain Research, University of Tübingen

Language: English

Topic: Transcranial Magnetic Stimulation Studies

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,430

Funders: Shanghai Municipal Health Commission, National Natural Science Foundation of China, Hong Kong Polytechnic University, China Scholarship Council, Young Scientists Fund

Awards: G4676450758, G5474714703, G7227657624, G7967138684

OpenAlex ID: W4414997236

FWCI: 0.591

Cites: 10

Cited by: 2

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