Work

Brachytherapy for choroidal metastasis secondary to primary urethral adenocarcinoma of Müllerian origin: A case report

Year: 2025

Type: article

Abstract: Purpose: To report a case of choroidal metastasis originating from primary urethral adenocarcinoma of Müllerian origin. Case presentation: A 67-year-old female patient with a history of primary urethral adenocarcinoma presented with progressive pain, flashes, and floaters in her right eye, prompting ophthalmic evaluation. Imaging, including fundus examination, ultrasonography, and optical coherence tomography, revealed an amelanotic choroidal mass associated with subretinal fluid. Biopsy confirmed choroidal metastasis from primary urethral adenocarcinoma. Tumor regression was achieved after brachytherapy. Conclusion: This case highlights the atypical metastatic behavior of urethral adenocarcinoma and emphasizes vigilance in recognizing potential ocular involvement in patients with rare malignancies. Further research is warranted to improve diagnosis and treatment. Categories: Oncology, Ophthalmology, Pathology.

Source: American Journal of Ophthalmology Case Reports

DOI: 10.1016/j.ajoc.2025.102450

Authors: Adriana P. Pérez Negrón, Victor M. Villegas, Camille L. Santiago-Negron, Maria J. Marcos-Martinez, Timothy G. Murray

Institutions: University of Puerto Rico System, University of Puerto Rico, Medical Sciences Campus

Language: English

Topic: Ocular Oncology and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,590