Work

Noninvasive longitudinal assessment of early-stage Duchenne muscular dystrophy: In vivo diaphragm imaging in mdx mice

Year: 2025

Type: article

Abstract: =0.54,P=0.025), supporting fibrosis as a primary factor driving changes in diaphragm viscoelastic properties. These findings establish US-SWEI as a noninvasive, feasible approach for monitoring respiratory muscle health and advancing preclinical DMD research. By identifying early-stage changes in diaphragm properties, this approach enables the development of therapeutic interventions targeting respiratory complications. Furthermore, US-SWEI presents a potential avenue for assessing and monitoring neuromuscular diseases.

Source: Ultrasonics

DOI: 10.1016/j.ultras.2025.107846

Authors: Jeehyun Lee, Nia O. Myrie, Woojin M. Han, Young C. Jang, Andrés J. García, Stanislav Emelianov

Institutions: Georgia Institute of Technology, Emory University, The Wallace H. Coulter Department of Biomedical Engineering, Icahn School of Medicine at Mount Sinai

Language: English

Topic: Ultrasound Imaging and Elastography

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,680