Year: 2025
Type: article
Study design: Case Report
Abstract: Objective: Hypoglycemia is a challenging clinical condition with a broad differential diagnosis, particularly in patients without diabetes. Identifying the underlying etiology is crucial, as management strategies vary significantly. Case Report: We report a case of severe postprandial hypoglycemia in a 19-year-old woman that developed shortly after an uncomplicated cholecystectomy. Extensive evaluation ruled out insulinoma, autoimmune hypoglycemia, and factitious causes. Discussion: The temporal relationship with surgery, postprandial symptom pattern, and unremarkable imaging suggested bile acid-mediated metabolic dysregulation due to altered bile enterohepatic circulation. The patient responded well to dietary modification and acarbose therapy. Conclusion: This case highlights the need to consider cholecystectomy in the differential diagnosis of postprandial hypoglycemia, especially when classic etiologies are excluded.
Source: AACE Endocrinology and Diabetes
Authors: Weiwei Zhao, Jasmine Kaur, Lubna Mirza
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4415018915