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Spatial Conformation of Ionizable Lipids Regulates Endosomal Membrane Disruption

Year: 2025

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.5c10908

Authors: Yu Zhao, Yu Zhao, Zhiyuan Qu, Markéta Paloncýová, Zeyu Wang, Benson Weng, Yuchen Zhao, Yuchen Zhao, Lihan Liu, Donghui Song, Douglas Wich, Michal Otyepka, Qiaobing Xu

Institutions: Tufts University, Zhejiang University, Regional Centre of Advanced Technologies and Materials, Palacký University Olomouc, VSB - Technical University of Ostrava

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: European Commission, European Cooperation in Science and Technology, Ministerstvo Školství, Mládeže a Tělovýchovy, Grantová Agentura České Republiky, Zhejiang University, European Regional Development Fund, National Heart, Lung, and Blood Institute

Awards: G1153767801, G1761812275, In-silico Workflow for Lipid-Mediated Active Pharmaceutical Ingredients Delivery Systems, G2162647311, G4358140732, G535059049

OpenAlex ID: W4415023844

FWCI: 2.791

Cites: 47

Cited by: 11

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