Work

Metastasis of Neuroendocrine Carcinoma Masquerading as a Chalazion

Year: 2025

Type: article

Abstract: Introduction: Nonhealing or rapidly growing lesions should raise suspicion for malignancy, especially in a patient with a prior history of cancer. The purpose of this case was to highlight the importance of a thorough clinical history. A high index of suspicion and low threshold for biopsy are important, as is a fast diagnosis, as they can make a difference in adequate treatment and prognosis. Case Presentation: We present a case of a 46-year-old female with a history of invasive ductal carcinoma of the breast presenting with a rapidly growing painless right lower eyelid lesion with biopsy remarkable for a high-grade neuroendocrine carcinoma suspected to be a result of metastasis with rare transformation of breast ductal carcinoma. Conclusion: She had an eyelid lesion recurrence less than 2 months after biopsy and excision, demonstrating the importance of early detection and biopsy with immunohistochemistry to target malignant cells and improve life quality and expectancy.

Source: Case Reports in Ophthalmology

DOI: 10.1159/000547525

Authors: Sofía Ramos-Bartolomei, José López-Fontanet, Sofía Muns-Aponte, José Raúl Montes, Miguel Noy

Institution: University of Puerto Rico, Medical Sciences Campus

Language: English

Topic: Metastasis and carcinoma case studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,030