Work

Comparative analysis of antibacterial activity of fatty acid from Vietnamese coconut oils produced by hot-extracted and cold-pressing methods

Year: 2025

Type: article

Abstract: This study investigated the antibacterial activity of fatty acids (FAs) extracted from coconut oil against Staphylococcus aureus and Methicillin-resistant S. aureus (MRSA). The FAs exhibited inhibitory effects at concentrations ≥5%, producing inhibition zones of 4 mm and above. Increasing concentration did not yield a proportional enhancement, indicating a non–dose-dependent effect. MRSA displayed slightly greater susceptibility than S. aureus at equivalent concentrations. Significant differences among concentrations were confirmed (p < 0.01). Although overall activity was comparable between cold-pressed (CCO) and hot-extracted coconut oil (HCO), FAs derived from CCO showed stronger inhibition, with minimum inhibitory concentrations (MICs) of 0.39% for both strains, compared to 0.78% for HCO against S. aureus. The superior efficacy of CCO-derived FAs likely reflects better preservation of medium-chain fatty acids—particularly lauric, capric, and caprylic acids—known for antimicrobial properties. These results highlight the influence of processing methods on the antibacterial efficacy of coconut oil–derived fatty acids.

Source: The University of Danang - Journal of Science and Technology

DOI: 10.31130/ud-jst.2025.23(9b).497

Authors: Doan Ngoc Tra My, Nguyen Thi Yen Phuong, Huynh Hoang Viet, Phan Thi Cuc, Le Ly Thuy Tram

Institution: University of Da Nang

Language: English

Topic: Coconut Research and Applications

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: diamond

Funder: Đại học Đà Nẵng